Berberine (anciennement Berberine HCl) · 500 mgProvides 500 mg of berberine hydrochloride per capsule, the dose used in clinical trials for glucose and lipid control. Hypoglycemic effects through multiple mechanisms, including improvement of insulin sensitivity Favorable effects on blood lipids, including a reduction in triglycerides and total and LDL cholesterol 9 Activation of Nrf 2, a key regulator of antioxidant gene transcription and prevention of glucose induced neurotoxicity. Extract of